Skincare / hyaluronic acid
hyaluronic acid
Evidence for skincare, scored from the published research.
skin hydration
promising83/100 Evidence ScoreConfidence: high4 studies2 RCTs
Multiple human studies report a positive effect.
- 3 human studies (836 participants total)
- Studies point in broadly the same direction
References (4)
- Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study.randomized controlled trial (RCT) · Nutrients · 2021
- Hyaluronic acid and HA-modified cationic liposomes for promoting skin penetration and retention.in vitro study · Journal of controlled release : official journal of the Controlled Release Society · 2023
- Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysis.meta-analysis · Indian journal of dermatology, venereology and leprology · 2025
- Oral sodium hyaluronate improves skin hydration, barrier function and signs of aging: a randomized, double-blind, placebo-controlled trial in 150 healthy adults.randomized controlled trial (RCT) · Scientific reports · 2025
Evidence Scores are computed mechanically from the published research (PubMed / Semantic Scholar / OpenAlex): study design, participant numbers, and consistency across studies. An LLM is used only to extract study data, never to decide a score.
This is research-based information, not medical advice, and not a diagnosis. Consult a qualified professional about your own situation.