- Research has been reported showing a positive effect on skin barrier function.
- The evidence score is 7, but reliability is very limited.
- This information is for those concerned about skin moisture retention and barrier function.
Niacinamide is an ingredient being examined for topical application to the skin.
Its properties are discussed in fields related to cosmetics.
Research results have shown that applying niacinamide to the skin may help stabilize barrier function. In other words, this is a report suggesting it may support the skin's protective power.
This study investigated the changes that occur when niacinamide is applied to the skin. Specifically, it examined the degree to which moisture escapes from the skin and the amount of moisture contained in the stratum corneum, the outermost layer of the skin.
From a technical standpoint, changes such as a reduction in transepidermal water loss (TEWL: the phenomenon in which moisture evaporates and escapes from the skin) and an increase in the water content of the stratum corneum (the outermost layer of the skin, which serves as a barrier) were reported.
An evidence score of 7 is shown, but reliability should be described as very limited. This number is an index of the strength of scientific evidence, but there is only 1 study behind this information. Therefore, this result alone does not determine anything conclusively, and it is appropriate to regard it as just one research case.
This study was conducted using a format called "other." This refers to a design classified as other (a research method carried out in a form different from a typical controlled experiment). By contrast, the method commonly used in clinical trials is the randomized controlled trial (a reliable research method that eliminates bias from conditions by dividing subjects into groups). Because this study did not use such a rigorous comparison, caution is needed when interpreting the results.
In addition, this data does not specify the number of participants or the specific study duration. As a result, it is not possible to determine the details of under what conditions, or over what length of time, the changes occurred. Including this lack of information, the study has limitations. Some people may see no effect, and it may not suit some people's skin.
There is a report on the possibility that niacinamide contributes to skin hydration. In other words, it may be involved in the mechanism that retains moisture on the skin's surface.
This study showed changes resulting from topical application (applying directly to the skin). Specifically, movement was observed suggesting that the skin surface's ability to retain moisture was being adjusted.
According to a specialized report, an increase in moisture within the stratum corneum was confirmed. This suggests the possibility that it may help stabilize the skin's barrier function.
| Study | Design | Number of Participants | Duration | Main Result |
|---|---|---|---|---|
| Journal of cosmetic dermatology (2004, PMID:17147561) | Other study design | Not reported | Not reported | A positive effect was reported |
The number of participants is listed as 0. Information on participant characteristics is also not provided.
Because the details of the participants are unknown, there is limited material for judging whether this study's results apply to you.
There is 1 study.
The study design is classified as "other."
The reliability of the research is reported to be very limited.
What effect has niacinamide been reported to have on skin barrier function?
Research has been reported showing that applying niacinamide affects the water content of the stratum corneum. There are also reports of a reduction in transepidermal water loss.
How reliable is the research on niacinamide?
The reliability of the reported research is very limited. There is only 1 study.
How many studies exist on niacinamide?
There is 1 research report on niacinamide. No further studies are included in this data.
One study has reported the possibility that niacinamide may help stabilize skin barrier function. The evidence score is 7, but reliability remains very limited. Please remember that the information in this article is based on only one set of research data. Try using a self-check assessment to check your current skin condition.